Light-triggered syneresis of a water insoluble peptide-hydrogel effectively removes small molecule waste contaminants
نویسندگان
چکیده
منابع مشابه
Light-activated hydrogel formation via the triggered folding and self-assembly of a designed peptide.
Photopolymerization can be used to construct materials with precise temporal and spatial resolution. Applications such as tissue engineering, drug delivery, the fabrication of microfluidic devices and the preparation of high-density cell arrays employ hydrogel materials that are often prepared by this technique. Current photopolymerization strategies used to prepare hydrogels employ photoinitia...
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The ability to control drug dosing in terms of quantity, location, and time is a key goal for drug delivery science,1 as improved control maximizes therapeutic effect while minimizing side effects.2 Systems responsive to a stimulus such as temperature,3 pH,4 applied magnetic5 or electrical6 field, ultrasound,7 light,8 or enzymatic action9 have been proposed as triggered delivery systems. Howeve...
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We describe a new dipeptide hydrogel based on an oligophenylene vinylene core. After gelation, the initial network evolves, expelling solvent and resulting in syneresis. We describe this process and the effects in the bulk properties of the material.
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A set of four phenylalanine analogues experiences diffusion retardation when transferred from phosphate-buffered saline into a peptide hydrogel of the same pH and ionic strength. The extent of retardation increases linearly with logP(oct), their lipophilicity.
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Removal of pathogenic organisms from reprocessed surgical instruments is essential to prevent iatrogenic infections. Some bacteria can make persistent biofilms on medical devices. Contamination of non-disposable equipment with prions also represents a serious risk to surgical patients. Efficient disinfection of prions from endoscopes and other instruments such as high-resolution cameras remains...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2020
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c9cc09225k